I discuss old unresolved problems in theoretical physics that can be simulated by NISQ (noisy intermediate scate quantum) devices, in particular, the puzzle of normal state of bose liquids at large densities and low temperatures as well as the diffusion (or the absence of it) in the non-integrable one dimensional quantum systems. I review the parameters of the existing qubit devices and argue that these problems can be  simulated by these devices that can be represent spin ladders or chains at high and low temperatures. I show that the available sizes already exceed those for which direct simulation by classical computer is possible.